Mitaur Int J Gynecol Cancer. Due to its higher spatial resolution and anatomical proximity to the study area, transvaginal ultrasound provides a detailed study of uterine lesions, including the morphology and degree of invasion 2. However, if metastasis is detected, the focus shifts to choriocarcinoma. Patients with more advanced disease can present with an enlarged uterus, with lobulated, heterogeneous contours, or a pelvic mass that extends to adjacent organs Behrman HR, et al. Another patient bled from an extensive vaginal metastasis that could only be treated with hypogastric arterial ligation. Studies have shown that nodules can persist after effective chemotherapy, without affecting the prognosis Gillespie AM, et al.

Author:Akizilkree Tusida
Language:English (Spanish)
Published (Last):21 November 2010
PDF File Size:9.59 Mb
ePub File Size:19.93 Mb
Price:Free* [*Free Regsitration Required]

Gardajinn Shortened duration of human chorionic gonadotrophin surveillance following complete or partial hydatidiform mole: Radiology of gestational trophoblastic neoplasia. Current advances in the management of gestational trophoblastic disease.

The images seen on an MRI scan have varying characteristics Trofohlastica 12depending on the duration of the associated bleeding 20, When combined with Doppler flow studies, it is useful not only in the evaluation of GTN but also in the evaluation of the response to treatment and in the detection of GTN recurrence. Rev Assoc Med Bras. The role of repeat uterine evacuation in the management of persistent gestational trophoblastic disease. Low risk of relapse after achieving undetectable HCG levels in women with complete molar pregnancy.

Gestational trophoblastic disease II: Even after effective chemotherapy treatment, lung nodules can still be seen on chest X-rays. Such abnormalities trofobblastica best viewed in the second trimester. Unlike invasive mole and choriocarcinoma, PSTT is distinguished by its relative chemoresistance and the potential need for surgical treatment 2, Two years after the episode, the patient achieved a new, normal pregnancy.

It is known that a low PI indicates a higher number of arteriovenous communications and greater neovascularization. Myometrial invasion can be suspected when the lesion crosses the myoendometrial border and the transitional zone becomes undefined. How gestacioal cite this article. Doenca Trofoblastica Gestacional Risk of partial and complete hydatidiform festacional pregnancy in relation to maternal age.

The accuracy of first trimester ultrasound in the diagnosis of hydatidiform mole. In such cases, partial hydatidiform mole with trisomy is differentiated by identifying a separate, normal, placenta 1,2, Because the patient was clinically stable and there was a fetal heartbeat, we opted for watchful waiting, trofoblaztica fetal death was confirmed at 14 weeks of pregnancy, indicating the induction of a molar abortion. Although of limited clinical significance, micrometastases can be seen scattered diffusely throughout the lung parenchyma.

Chemotherapy is started even before histological confirmation has been gestzcional, and both entities are treated with the same chemotherapy regimen 1.

In patients classified as high risk and showing metastasis to the lung or vagina, abdominal CT is recommended In the hypervascular form, the tumor has an isointense signal on T1-weighted images, a slightly hyperintense signal on T2-weighted images, and avid uptake after the administration of contrast gadolinium. Dodna sites are reported to be affected, including the spleen, kidneys, gastrointestinal tract, and skin. Human chorionic gonadotropin and associated molecules. Studies have shown that nodules can persist after effective chemotherapy, without affecting the prognosis Relationship between blood and urine concentrations of intact human chorionic gonadotropin and its free subunits in early pregnancy.

However, the treatment is preceded by anatomical staging Table 1which allows the results to be compared among various referral centers 20as well as allowing the determination of the FIGO risk trofoblawtica for chemoresistance 7as shown in Table 2, which is fundamental to choosing the treatment strategy, except in cases of PSTT or ETT Although biopsy is contraindicated because of the risk of fatal bleeding 43these lesions can respond to selective chemoembolization.

Angiography in GTN Conventional angiography can be used for the embolization of vaginal and liver metastases. Current FIGO staging for cancer of the vagina, fallopian tube, ovary, and gestational trophoblastic neoplasia. In the hypovascular form, the tumor has less volume, as well as a higher signal intensity on T1- and T2-weighted images, and a lower rate of uptake of contrast.

One of frofoblastica most common treatment regimens is the combination of etoposide, methotrexate, and actinomycin-D, alternating weekly with cyclophosphamide plus vincristine Because it is an unusual and serious disease that affects women of reproductive age, as well as because its appropriate treatment results in high cure rates, it is crucial that radiologists be familiar with gestational trophoblastic disease, in order to facilitate its early diagnosis and to ensure appropriate follow-up imaging.

Choriocarcinoma and partial hydatidiform moles. The diagnosis of molar trofob,astica by However, if metastasis is detected, the focus shifts to choriocarcinoma. However, the imaging findings are nonspecific and can be difficult to distinguish from those of, for example, retained products of conception or an ectopic pregnancy with GTN Expert Rev Gestacioal Diagn.

Related Articles.


Doença Trofoblástica Gestacional









Doença trofoblástica gestacional


Related Articles