BY-LAW 639-05 PDF

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Vudoll See the van der Burg patent, column 1, lines 43 through The very prior art reference here relied on by the examiner, however, undermines the prima facie case because the reference teaches that compounds similar in structure in this art do not possess similar properties.

Pyrrolidino and piperidino compounds contain a 5- and 6-membered ring, respectively. Skip to main content. R1 represents hydrogen, lower alkyl, cycloalkyl-lower alkyl of not more than 10 carbon atoms, lower alkenyl, lower alkynyl, di-lower alkylamino -lower alkyl, hydroxy lower alkyl, alkoxy lower alkyl, alkanoyloxy lower alkyl having 4 to 11 carbon atoms, lower alkylthio-lower alkyl, phenyl-lower alkyl, phenyl- lower alkyl substituted by halogen with an atomic number up to 35, lower alkyl, lower alkoxy, methylenedioxy, and trifluoromethyl, or lower alkanoyl, the ring A is unsubstituted or substituted by halogen with an atomic number up to 35, lower alkyl, hydroxyl, lower alkoxy, alkanoyloxy having carbon atoms, lower alkylthio, trifluoromethyl or cyano, X represents 0, S, methylene, a direct bond or a divalent radical of the partial formula.

Van der Burg discloses that the known pyrrolidino and piperidino compounds possess diametrically opposite utilities. A compound which is neither because the depressant and anti-depressant effects counteract each other? What utility would a person having ordinary skill in the art have expected for the azepine or 7-membered ring compound? In obviousness rejections based on close similarity in chemical structure, the prima facie case of obviousness rises from the expectation that compounds similar in structure will have similar properties.

Claims 17, 11 and 14 are representative. Application for Patent filed September 29,Serial No. This fact is not in dispute. A pharmaceutical composition useful in the by-lww of states of agitation in a warmblooded animal comprising a therapeutically effective amount of an azatetracyclic compound according to claim 17, or a pharmaceutically acceptable acid addition salt thereof together with a pharmaceutical carrier. A method of treating states of agitation in a warmblooded animal which comprises administering to said animal a therapeutically effective amount of a compound according to claim 17, or a pharmaceutically acceptable acid addition salt thereof.

In re Payne, F. The sole by-lww presented for is whether the examiner correctly rejected claims 6, 7, 9 and 11 through 20 under 35 U. Quite clearly, the very reference relied on by the examiner teaches that compounds similar in structure in this art do not possess similar properties.

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Faezahn Law Document English View A pharmaceutical composition useful in the treatment of states of agitation in a warmblooded animal comprising a therapeutically effective amount of an compound according to claim 17, or a pharmaceutically by-laaw acid addition salt thereof together with a pharmaceutical carrier. As described therein, the pyrrolidino derivatives are useful in treating conditions of stress and agitation whereas the piperidino compounds are useful in treating depressed patients. In obviousness rejections based on close similarity in chemical structure, the prima facie case of obviousness rises from the expectation that compounds similar in structure will have similar properties. More specifically, the issue is whether the examiner has established that the claimed subject matter would have been prima facie obvious in view of the disclosure of van der Burg.

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BY-LAW 639-05 PDF

Vudoll See the van der Burg patent, column 1, lines 43 through The very prior art reference here relied on by the examiner, however, undermines the prima facie case because the reference teaches that compounds similar in structure in this art do not possess similar properties. Pyrrolidino and piperidino compounds contain a 5- and 6-membered ring, respectively. Skip to main content. R1 represents hydrogen, lower alkyl, cycloalkyl-lower alkyl of not more than 10 carbon atoms, lower alkenyl, lower alkynyl, di-lower alkylamino -lower alkyl, hydroxy lower alkyl, alkoxy lower alkyl, alkanoyloxy lower alkyl having 4 to 11 carbon atoms, lower alkylthio-lower alkyl, phenyl-lower alkyl, phenyl- lower alkyl substituted by halogen with an atomic number up to 35, lower alkyl, lower alkoxy, methylenedioxy, and trifluoromethyl, or lower alkanoyl, the ring A is unsubstituted or substituted by halogen with an atomic number up to 35, lower alkyl, hydroxyl, lower alkoxy, alkanoyloxy having carbon atoms, lower alkylthio, trifluoromethyl or cyano, X represents 0, S, methylene, a direct bond or a divalent radical of the partial formula.

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The single prior art reference relied on by the examiner is: R1 represents hydrogen, lower alkyl, cycloalkyl-lower alkyl of not more than 10 carbon atoms, lower alkenyl, lower alkynyl, di-lower alkylamino -lower alkyl, hydroxy lower alkyl, alkoxy lower alkyl, alkanoyloxy lower alkyl having 4 to 11 carbon atoms, lower alkylthio-lower alkyl, phenyl-lower alkyl, phenyl- lower alkyl substituted by halogen with an atomic number up to 35, lower alkyl, lower alkoxy, methylenedioxy, and trifluoromethyl, or lower alkanoyl, the ring A is unsubstituted or substituted by halogen with an atomic number up to 35, lower alkyl, hydroxyl, lower alkoxy, alkanoyloxy having carbon atoms, lower alkylthio, trifluoromethyl or cyano, X represents 0, S, methylene, a direct bond or a divalent radical of the partial formula. As described therein, the pyrrolidino derivatives are useful in treating conditions of stress and agitation whereas the piperidino compounds are useful in treating depressed patients. In re Payne, F. Pyrrolidino and piperidino compounds contain a 5- and 6-membered ring, respectively. Claims 17, 11 and 14 are representative.

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Kajinos R1 represents hydrogen, lower alkyl, cycloalkyl-lower alkyl of not more than 10 carbon atoms, lower alkenyl, lower alkynyl, di-lower alkylamino -lower alkyl, hydroxy lower alkyl, alkoxy lower alkyl, alkanoyloxy lower alkyl having 4 to 11 carbon atoms, lower alkylthio-lower alkyl, phenyl-lower alkyl, phenyl- lower alkyl substituted by halogen with an atomic number up to 35, lower alkyl, lower alkoxy, methylenedioxy, and trifluoromethyl, by-lzw lower alkanoyl, the ring A is unsubstituted or substituted by halogen with an atomic number up to 35, lower alkyl, hydroxyl, lower alkoxy, alkanoyloxy having carbon atoms, lower alkylthio, trifluoromethyl or cyano, X ny-law 0, S, methylene, a direct bond or a divalent radical of the partial formula. What utility would a person having ordinary skill in the art have expected for the azepine or 7-membered ring compound? Quite clearly, the very reference relied on by the examiner teaches that compounds similar in structure in this art do not possess similar properties. Skip to main content. This fact is not in dispute. The very prior art reference here relied on by the examiner, however, undermines the prima facie case because the reference by-lww that compounds similar in structure in this art do not possess similar properties.

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